Scientists reveal splicing-based mechanism driving therapy resistance in pediatric acute myeloid leukemia by Chinese Academy of Sciences edited by Sadie Harley, reviewed by Robert Egan Editors' notes ...
Genes contain the essential building instructions for life, guiding cells on which amino acids to assemble in what sequence to produce specific proteins. The human genome codes for about 20,000 such ...
A recent study highlights the pivotal role of alternative splicing in controlling plant secondary metabolism, which is crucial for producing bioactive compounds with significant medicinal and ...
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Study reveals a key mechanism for controlling the activity of neuronal identity regulators
A team of researchers has identified a mechanism that regulates the production of two different proteins from the same gene. Researchers from the Institute for Neurosciences, a joint center of the ...
Researchers developed molecules, called splice-switching oligonucleotides (SSOs) that bind to the RNA molecules encoding a protein known as REST. In neuroendocrine tumors, these RNAs are incorrectly ...
Collaboration with UMass Chan Medical School confirmed FMR1-217 as well as an RNA-targeted mechanism to restore functional FMRP protein to develop potential treatments for FXS QurAlis’ preliminary ...
In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...
A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, in collaboration with ...
Pediatric acute myeloid leukemia (AML) is one of the most common acute leukemias in children. While treatment outcomes have improved in recent years, approximately 30% of patients relapse following ...
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