Brianna Bibel on Instagram: "Targeted protein degradation (via PROTACs, molecular glues, conditional degron tags etc.) https://youtube.com/shorts/vr_FeRVypfE Our bodies use the Ubiquitin-Proteasome System (UPS) to target unwanted proteins (via the addition of chains of a small protein called ubiquitin) to the proteasome (protein-shredder). Much more on the UPS and how it works “normal-function-wise” in a past post I will link to. But today I want to talk about how we can hijack this system to se