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epomedicine.com
Heme Synthesis and Defects Simplified
Heme is a ferro-proto-porphyrin. 1. Glycine + Succinyl-CoA = δ-ALA (Amino-Levulinic Acid) 2. ALA leaves mitochondria into the cytosol 3. ALA + ALA or 2 X ALA = Porphobilinogen We now have a pyrrole…
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